A DISRUPTED FOXP3 TRANSCRIPTIONAL SIGNATURE UNDERPINS SYSTEMIC REGULATORY T CELL INSUFFICIENCY IN EARLY PREGNANCY FAILURE

A disrupted FOXP3 transcriptional signature underpins systemic regulatory T cell insufficiency in early pregnancy failure

Summary: Regulatory T (Treg) cell defects are implicated in disorders of embryo implantation and placental development, but the origins of Treg cell dysfunction are unknown.Here, we comprehensively analyzed the phenotypes and transcriptional profile of peripheral blood Treg cells in individuals with early pregnancy failure (EPF).Compared to mozelle

read more



Behavioural symptoms of attention deficit/hyperactivity disorder in preterm and term children born small and appropriate for gestational age: A longitudinal study

Abstract Background It remains unclear whether it is more detrimental to be born too early or too small in relation to symptoms of attention chrome cologne set deficit/hyperactivity disorder (ADHD).Thus, we tested whether preterm birth and small body size at birth adjusted for gestational age are independently associated with symptoms of ADHD in ch

read more